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Monday, July 27, 2020 | History

1 edition of Lipofuscin and Ceroid Pigments found in the catalog.

Lipofuscin and Ceroid Pigments

Lipofuscin and Ceroid Pigments

State of the Art 1995 (Journal - Gerontology, , Vol 41, Suppl. 2)

  • 250 Want to read
  • 19 Currently reading

Published by S. Karger AG (Switzerland) .
Written in English

    Subjects:
  • Biochemistry,
  • Geriatric medicine,
  • Human reproduction, growth & development,
  • Molecular biology,
  • General,
  • Medical / Nursing,
  • Science/Mathematics

  • Edition Notes

    ContributionsK. Kitani (Editor), Gwen O. Ivy (Editor), H. Shimasaki (Editor)
    The Physical Object
    FormatPaperback
    Number of Pages330
    ID Numbers
    Open LibraryOL12930556M
    ISBN 103805562594
    ISBN 109783805562591

    Lipofuscin is a brownish pigment left over from the breakdown and absorption of damaged blood cells. Lipofuscin is found in heart muscle and smooth muscles. It is also called the aging pigment. COVID Resources. Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle .

    Pathology - Pigments. STUDY. Flashcards. Learn. Write. Spell. Test. PLAY. Match. Gravity. Created by. nkrrrr. Terms in this set (49) anthracosis due to carbon inhalation exogenous pigment. Lipofuscin/ceroid. Lipofuscin/ceroid. illustrates the ability of this pigment to fluoresce when exposed to UV light. This pigment has accumulated in. Lipofuscin is a common term for 'aging pigments'. The word Lipofuscin is derived from the Latin word 'fuscus' = dark or sombre. Lipofuscin is an insoluble lipid pigment and is also known as 'wear and tear pigment' as it is usually present in the cells of elderly persons.

      Both endogenous and exogenous pigment can occur in hepatocytes, but pigmentation occurs more often in Kupffer cells. Pigment may be prominent in portal areas. Identification of hepatic pigment typically requires multiple special stains. Different pigments frequently contain some iron and will thus have variable positivity with Prussian blue stain. Medical definition of ceroid: a yellow to brown pigment that is similar in composition to lipofuscin and accumulates in cells chiefly in diseased states and under experimental conditions.


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Lipofuscin and Ceroid Pigments Download PDF EPUB FB2

Lipofuscin (ceroid, lipochrome) Ceroids, lipofuscin or lipochromes are seen in the livers of untreated rodents, monkeys, dogs and humans particularly in older individuals (Figure ).

The accumulation of these pigments can be accelerated by treatment with drugs and chemicals, trauma, circulatory disturbances and dietary abnormalities. Get this from a library.

Lipofuscin and ceroid pigments. [Eduardo A Porta;] -- Some two dozen papers, plus summaries of another half dozen, examine aspects of recent developments in the biogenesis, properties, and nosologic implications of the autofluorescent lipopigments.

: Lipofuscin and Ceroid Pigments (Advances in Experimental Medicine & Biology) (): Porta, Ernesto: BooksFormat: Hardcover. : Lipofuscin and Ceroid Pigments (Advances in Experimental Medicine and Biology) (): Ernesto Porta: Books.

The sections cover lipofuscin, ceroid pigments in nutritional and environmental pathology, ceroid in genetic disorders, and in vitro systems of lipopigment formation. Annotation c. Book News, Inc., Portland, OR () BooknewsPrice: $   Autofluorescent lipofuscin and lipofuscin-like pigments.

Indeed, alongside with riboflavin (vitamin B 2) and among the several previously mentioned endogenous biomolecules exhibiting a fluorophore-like activity, 1 autofluorescent lipofuscin and lipofuscin-like pigments may also occur in the cell cytoplasmic compartment, with Lipofuscin and Ceroid Pigments book heterogeneous substances also Cited by: Lipofuscin is a common term for aging pigments, whereas ceroid is used to describe pathologically derived storage material, for example, in the neuronal ceroid lipofuscinoses (NCLs).

NCLs are a family of neurodegenerative diseases that are characterized by an accumulation of autofluorescent storage material (ceroid) in the lysosome, which has Cited by: ceroid: (sē'royd), A waxlike, golden, or yellow-brown pigment first found in fibrotic livers of choline-deficient rats, and also known to be present in some cirrhotic livers (and certain other tissues) of human beings.

Ceroid is acid fast, insoluble in fat solvents, and probably a type of lipofuscin although differing from true lipofuscins.

Lipofuscin: The “Wear and Tear” Pigment Sabrina S. Seehafer David A. Pearce Many substances fluoresce spontaneously (autofluoresce, i.e., emit light of a particular wavelength) when illuminated by light of a different wavelength.

Pathologists are well used to observing autofluorescence (AF) in certain cells, such as macrophages, when viewing specimens with a. lipofuscin: [ lip″o-fu´sin ] 1. a yellow to brown, granular, iron-negative lipid pigment found particularly in muscle, heart, liver, and nerve cells; it is the product of cellular wear and tear, accumulating in lysosomes with age.

lipochrome. Neuronal ceroid lipofuscinosis is the general name for a family of at least eight genetically separate neurodegenerative lysosomal storage diseases that result from excessive accumulation of lipopigments in the body's tissues.

These lipopigments are made up of fats and name comes from the word stem lipo- which is a variation on "lipid" or "fat", and from the term Specialty: Endocrinology. PDF | On Apr 1,D Riga and others published Lipofuscin and ceroid pigments in aging and brain pathology.

A review. Biochemical and morphological properties | Find, read and cite all the. Lipofuscin, Lipofuscin-Like Pigments and European Journal of Histochemistry ; volume [page 72 ] [European Journal of Histochemistr y Author: Giovanni Di Guardo. Autofluorescent ceroid/lipofuscin-type pigments are usually classified and defined as follows: Lipofuscin is an intracellular, age-related, fluorescent, cytoplasmic, granular pigment.

It is mainly Cited by: 3. According to Aubrey's book, centrophenoxine doesn't work either. It seems that people were mistakenly calling ceroid lipofuscin. Here are some of what he cites. Ann N Y Acad Sci. Apr; Pigments in aging: an overview. Porta EA. Neuronal ceroid lipofuscinosis (NCL) refers to a group of conditions that affect the nervous system.

Signs and symptoms vary widely between the forms but generally include a combination of dementia, vision loss, and gh the NCLs were historically classified according to their age of onset and clinical symptoms, the most recent classification system is.

said that both pigments represent oxidative damage to organelles ceroid-containing neurdegenerative disortders are named ceroid lipsfuscinosis-use lipofuscin as the pigment in aging cells, and ceroid as the pigment seen in cells responding to various types of injury-use the term ceroid/lipofuscin.

Another Side Of Lipofuscin Age Pigments. By Atom Bergstrom. Atom’s Blog. Lipofuscin, the age pigments (plural) that clog up lysosomes, mitochondria, and the cytoplasm of cells, can’t form without polyunsaturated fatty acids, especially highly-unsaturated fatty acids (docosahexaenoic acid, docosapentaenoic acid, eicosapentaenoic acid, and alpha-linolenic acid).

The formation of lipofuscin and lipofuscin-like compounds is known to take place under a variety of pathophysiological conditions, such as oxidative stress and ageing, “two sides of the same coin” which are essentially characterized by a progressive unbalance between protein damage and cleaance, leading at its turn to an increased protein.

Medical definition of lipofuscin: a usually yellowish brown, pigmented, insoluble granule that contains protein and lipid and accumulates in cells (as of the heart, liver, or brain) as part of the normal aging process or sometimes in association with diseased states.

Lipofuscin, lipofuscin-like pigments and autofluorescence G. Di Guardo Faculty of Veterinary Medicine, University of Teramo, Italy Abstract A brief overview is here provided on lipofus-cin and lipofuscin-like substances, with partic-ular reference to their biological significance as well as to their cellular origin and patho-physiological role.

Little is known at present about the saccharide components of lipofuscin (age pigment) and ceroid pigments in situ. The purpose of this study was, therefore, to study in detail the lectin reactivities of lipofuscin in neurons and cardiac myocytes of old humans and rats. In addition, those of diverse ceroid pigments found in human aortic atheromas, in the livers of Cited by: Accumulation of ceroid (lipofuscin) pigment (arrows) in the cytoplasm of interstitial cells.

Comment: The pigment in the testis shown in Figure 1 and Figure 2 represents intracytoplasmic accumulation of ceroid pigment (lipofuscin), which is a light File Size: KB.